BENEFITS OF CREA-X4
- Includes various creatine salts and ethyl ester.
- Enhanced aqueous solubility and bioavailability of the salts.
- Creatine increases physical performance in successive bursts of short-term, high intensity exercise.
Unlike the SSRIs mentioned above, dapoxetine was developed specifically for treatment of PE and is the only SSRI approved for treatment of the condition. What sets dapoxetine apart from other SSRIs currently used off-label to treat PE is its pharmacokinetic profile. Briefly, the pharmacology of dapoxetine may be summarized as follows:
These pharmacokinetic characteristics make dapoxetine ideal for on-demand dosing, which reduces the probability of unwanted side effects. Previous Phase II studies identified the optimal dose to be 30 mg initially, with an increase to 60 mg (the maximum recommended dose) if required. Pharmacodynamic studies identified the optimal dose administration time to be 1–3 hours before sexual intercourse.